Brain fog, probiotics, and SIBO - Part 2 - Aspire Natural Health

Brain fog, probiotics, and SIBO – Part 2


In this Episode Dr. Gerstmar discusses:
-A study of brain fog, probiotics, and SIBO
-D-lactate – what it is and where to get it tested
-Stopping probiotics and what it did for people with brain fog
-Should you try D-lactate free probiotics?




For the research paper on Brain fog, probiotics, and SIBO, click HERE:



Hey Folks,

It’s Dr. Gerstmar from Aspire Natural Health

And in this quick video, part 2 of a 2 part series, on brain fog, probiotics, and SIBO.

Before we get going today, we need to take just a moment and recap a couple of things from part one.

The first is to remember that context matters.

Today we’re going to talk about how a recent study showed that probiotics can worsen brain fog. And that’s something I’ve also seen in the clinic as well. But it’s important to remember to put things in context. Not everyone with brain fog is going to have SIBO or bad reactions to probiotics. But it’s clear that some people do.

The second is to remember lactic acid. Most people think of lactic acid as the stuff that builds up in your muscles when you exercise and that’s true. But lactic acid can also be produced by your gut bacteria, and important probiotic bacteria like Lactobacillus and Bifidobacteria can make lactic acid. If lactic acid builds up to high levels it can cross into your brain causing brain fog, and has also been suggested to cause chronic fatigue as well.

In the study that we’re talking about today, and I will go ahead and put the link in the description for this video, 38 people who had gas and bloating were studied. Of those 38, 30 had brain fog and 8 did not. Everyone was given a SIBO test as well as measuring the levels of D-lactate in their urine.

The urinary D-lactate is a test most people have not heard about, and I did a little research to see if the D-lactate test was available through regular labs such as Quest or Labcorp, and unfortunately neither offer it. So it is extremely unlikely that a conventional doctor is going to do this test for you.

Where it is available are through tests called Organic Acid tests which are offered by companies such as Genova Diagnostics or Great Plains Laboratory.

What they found in these 38 people were that 12 tested positive for SIBO and 26 did not. And this tells us two things. First not everyone with gas and bloating is going to have SIBO. And second SIBO tests are far from perfect. That doesn’t mean they’re not useful, but that’s a topic for another day.

Overall they found that about 70% of the people with brain fog had SIBO, while about 30% of the people without brain fog had SIBO.

For the 30 people who had brain fog, 23 tested positive for high levels of D-lactate, and 7 did not. Of the 8 people who did not have brain fog, 2 showed high levels of D-lactate, and 6 did not.

So the majority of people who had brain fog tested positive for high levels of D-lactate.

Another major finding of the study was that all 30 people who were complaining of brain fog were taking probiotics.

So the researchers took everyone off probiotics and treated them with a heavy course of antibiotics. And what they found was that 85% of the people with brain fog saw major improvement.


So there you have it…

Let’s pull things together. If you’re suffering from brain fog and you’re taking probiotics, you might want to try stopping your probiotics for 1-4 weeks, and if things improve significantly than you might be a person for whom probiotics make things worse.

If that doesn’t help, you may want to get a SIBO test and an Organic Acid test done to help you evaluate whether excess D-lactate might be a big problem for you.

One last piece today, and that is you will see a number of brands of probiotics advertising that they are D-lactate free. The reality is that this is mostly a marketing claim right now and the data on whether they are really D-lactate free and whether they make a big difference in conditions like this or not just isn’t there. I’ve definitely seen some people that do better on D-lactate free products and others who don’t.

So this is where individualization comes into play. And armed with information like this you can see what works best for you, or hopefully you have or can work with a highly trained expert to help you get the results you want.

If you or anyone you know is dealing with IBS or Irritable Bowel Syndrome I’d like to offer you the Guide we’ve put together on how we treat IBS here at Aspire Natural Health, all you need to do is click the button below and fill out the short form, and we’ll happily send that to you for FREE. So please, click down below.

At Aspire Natural Health we are experts at treating digestive issues and autoimmune diseases. If that’s you, we’d love to connect.

We offer a no-obligation no-pressure chat to see if we can help you, and if we’re the right fit to work together.

If we are, we’ll move forward, and if we’re not, we’ll do our best to connect you with the person who can best help you.

You have nothing to lose, so call us now at 425-202-7849 or email us at

Until next time folks…Take care!


At Aspire Natural Health we are experts at helping people suffering with digestive issues and autoimmunity.

Are you looking for help?

Email us at or call us at 425-202-7849.

The first step of our process is to see if we’re a good fit for one another. If we are, we’ll talk about next steps. If not, that’s okay, and we’ll do our best to help you find the right person.

Everything is no-obligation and no-pressure, so you don’t have to worry. You have nothing to lose!

Call us at 425-202-7849 or email us now!


Another Interesting post:

Can you use garlic to treat SIBO? Food vs Supplements

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