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DrG – “Here are 12 of the worst hormone disrupters, how they do their dirty deeds, and some tips on how to avoid them.” Read the linked article for more information.
6. Fire retardants
10. Perfluroinated chemicals
11. Organophosphate pesticides
DrG – A great article on gut bacteria, disease and health. First, a key point, “Conventional models…assume that microorganisms or their products are necessarily injurious to the host. In contrast, an evolutionary perspective suggests that host-microbial interactions are a symbiotic model and that disease results from the disruption of a mutually beneficial homeostatic state…one of the most important changes we can make is to supersede the 20th-century metaphor of war for describing the relationship between people and infectious agents…Yet, this intricate symbiotic relationship has had a darker side. Microorganisms are the trigger of a broad array of human diseases…For the physician, whose loyalties lie with the immediate interests of the species Homo sapiens, it is all too easy to lose sight of our evolutionary heritage and to seek victory, rather than accommodation, in approaching the ravages of human disease.”
Second, and more specifically, if our gut bacteria are really an “organ” of the body as they are often now considered, could LPS, instead of being a “toxin” really be a “hormone”. “LPS is a…component of the cell wall of gram-negative bacteria, which…are ubiquitous…in the gastrointestinal tracts of most animals….[LPS is the] best-studied trigger of the host inflammatory response…[LPS’] ubiquity during times of acute physiological stress is reminiscent of the patterns of release of such classic stress hormones as cortisol or epinephrine…although endotoxin is not produced by human cells, it is released from stores that are present in all humans in response to a variety of acute stresses…The interaction of LPS with cells of the host innate immune system is both intricate and specific…The details of this interaction are similar in many respects to that of an endogenous hormone whose evolutionarily conserved role is the support of innate immunity. In particular, disruption of the systems that facilitate recognition of LPS by the host can result in impairment of innate immune mechanisms, to the detriment of the host.”
DrG – Why is nearsightedness (myopia) getting worse in children? “Myopia isn’t an infectious disease, but it has reached nearly epidemic proportions in parts of Asia. In Taiwan, for example, the percentage of 7-year-old children suffering from nearsightedness increased from 5.8 percent in 1983 to 21 percent in 2000…The explosion of myopia is a serious public health concern, and doctors have struggled to identify the source of the problem. Nearsightedness has a strong element of heritability, but the surge in cases shows that a child’s environment plays a significant role…Researchers believe they are now closing in on a primary culprit: too much time indoors…Over the past few years, much myopia research has focused on substantiating, quantifying, and explaining the connection between time outdoors and proper ocular development…There isn’t yet broad agreement on why the outdoors might protect children from near-sightedness…Studies on rhesus monkeys, however, suggest that simple light exposure is the more likely explanation. While myopia is extremely uncommon among nonhuman primates, researchers can easily induce myopia by depriving infant monkeys of normal outdoor lighting levels. (Outdoor lighting is usually about 100 times more intense than what you get inside.) It’s no wonder that the most extreme changes in myopia prevalence over recent decades have occurred in sunny places like Singapore, where the difference between outdoor and indoor light intensity is most extreme…In the 1930s scientists observed that myopia was very rare in hunter-gatherer societies, and a 1960s study of native people in Alaska showed that older generations, who had not attended school, were much less likely to have myopia than younger generations, who had…Perhaps the new mantra should be: “Go outside, you’re blinding yourself in here.”
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